How to replace a Capillary Column in an Agilent GC/MS | Inlet & MSD Installation Step-by-Step
How to replace
a capillary GC column in an Agilent GC/MS.
In this hands-on video, I walk through capillary column installation from the inlet to the MSD transfer line.
Topics covered:
• Preparing the column for installation
• Making a clean, square column cut
• Installing the correct nut and ferrule
• Setting the correct column insertion depth at the inlet
• Installing the column into the MSD transfer line
• Avoiding leaks and poor positioning
• Checking the installation before returning the GC/MS to service
A new column can still give poor chromatography if it is installed incorrectly. Small errors in column cutting, ferrule installation, or insertion depth can lead to leaks, poor peak shape, unstable vacuum, retention-time problems, and loss of response.
This video is intended for analysts and laboratory staff who perform their own GC and GC/MS maintenance.
Vineta Mills Consulting
Practical GC and GC/MS maintenance, troubleshooting, chromatography, method development, and laboratory training.



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